AS 602801 (BentaMapiMod)
2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile
CAS: 848344-36-5
Molecular Formula: C25H23N5O2S
AS 602801 (BentaMapiMod) - Names and Identifiers
AS 602801 (BentaMapiMod) - Physico-chemical Properties
| Molecular Formula | C25H23N5O2S |
| Molar Mass | 457.55 |
| Density | 1.326 |
| Boling Point | 666.5±65.0 °C(Predicted) |
| pKa | 6.47±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Use | Bentamapimod, also known as AS602801 and PGL5001, is a JNK Inhibitor. AS602801 induces regression of endometriotic lesions in animal models. AS602801 interrupts immune pathways. Bentamapimod induced regression of endometriotic lesions in endometriosis rodent animal models without suppressing ER action. Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth of endometrial tissue at extrauterine sites. |
| Target | JNK1；JNK2；JNK3 |
AS 602801 (BentaMapiMod) - Reference
| Reference Show more | 1: Hussein M, Chai DC, Kyama CM, Mwenda JM, Palmer SS, Gotteland JP, D'Hooghe TM.c-Jun NH(2)-terminal kinase inhibitor bentamapimod reduces induced endometriosisin baboons: an assessor-blind placebo-controlled randomized study. Fertil Steril.2015 Dec 2. pii: S0015-0282(15)02106-8. doi: 10.1016/j.fertnstert.2015.11.022.[Epub ahead of print] PubMed PMID: 26654972. 2: Palmer SS, Altan M, Denis D, Tos EG, Gotteland JP, Osteen KG, Bruner-Tran KL,Nataraja SG. Bentamapimod (JNK Inhibitor AS602801) Induces Regression ofEndometriotic Lesions in Animal Models. Reprod Sci. 2016 Jan;23(1):11-23. doi:10.1177/1933719115600553. Epub 2015 Sep 2. PubMed PMID: 26335175. |
AS 602801 (BentaMapiMod) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.186 ml | 10.928 ml | 21.856 ml |
| 5 mM | 0.437 ml | 2.186 ml | 4.371 ml |
| 10 mM | 0.219 ml | 1.093 ml | 2.186 ml |
| 5 mM | 0.044 ml | 0.219 ml | 0.437 ml |
Last Update：2024-01-02 23:10:35
Supplier List
Spot supply
Product Name: AS-602801 Request for quotationCAS: 848344-36-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Bentamapimod Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: (1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: AS 602801 Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: AS-602801 Request for quotationCAS: 848344-36-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Bentamapimod Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: (1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: AS 602801 Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile Visit Supplier Webpage Request for quotationCAS: 848344-36-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History